Chronic Renal Failure, Cachexia, and Ghrelin
نویسندگان
چکیده
منابع مشابه
Chronic Renal Failure, Cachexia, and Ghrelin
Protein energy wasting is frequently observed in patients with advanced chronic renal failure and end-stage renal disease. Anorexia and reduced food intake are critical contributing factors and negatively impact on patients' survival. Ghrelin is a prophagic peptide produced by the stomach and acting at the hypothalamic level to increase the activity of orexigenic neurons. In patients with chron...
متن کاملElevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors.
BACKGROUND Ghrelin is a novel growth hormone (GH)-releasing peptide, isolated from the stomach, that may also cause a positive energy balance by stimulating food intake and inducing adiposity. We sought to investigate the pathophysiology of ghrelin in the cachexia associated with chronic heart failure (CHF). METHODS AND RESULTS Plasma ghrelin was measured in 74 patients with CHF and 12 contro...
متن کاملPlasma ghrelin and desacyl ghrelin concentrations in renal failure.
Ghrelin is a novel hormone that possesses growth hormone (GH)-releasing, cardiovascular, and metabolic activities. Ghrelin is a unique acylated polypeptide, and the naked peptide, desacyl ghrelin, does not have the activity. This study examines plasma ghrelin concentrations in 41 patients with mild to severe renal diseases. Two kinds of radioimmunoassays were used: amino-terminal immunoreactivi...
متن کاملChronic Renal Failure and Its effects on Serum Lipids
Background: Metabolic disturbances and dyslipidemia are among the most important medical problems in human society. Their effects on the mortality of coronary heart disease (CHD) have lead to many investigations about them. Materials and Methods: An epidemiologic cross-sectional study was carried out on 10136 persons selected randomly in Tehran urban district 13 with a minimum age of 20 years ...
متن کاملElevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure
Hideki Hiroyuki Okumura, Hiroshi Hosoda, Wataru Shimizu, Masakazu Yamagishi, Hideo Oya, Noritoshi Nagaya, Masaaki Uematsu, Masayasu Kojima, Yukari Date, Masamitsu Nakazato, : Relationships Between Ghrelin and Anabolic/Catabolic Factors Elevated Circulating Level of Ghrelin in Cachexia Associated With Chronic Heart Failure Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2001 American H...
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ژورنال
عنوان ژورنال: International Journal of Peptides
سال: 2010
ISSN: 1687-9767,1687-9775
DOI: 10.1155/2010/648045